Iron metabolism and maternal-fetal iron circulation
نویسندگان
چکیده
منابع مشابه
Fetal iron status regulates maternal iron metabolism during pregnancy in the rat.
Iron metabolism during pregnancy is biased toward maintaining the fetal supply, even at the cost of anemia in the mother. The mechanisms regulating this are not well understood. Here, we examine iron deficiency and supplementation on the hierarchy of iron supply and the gene expression of proteins that regulate iron metabolism in the rat. Dams were fed iron-deficient diets for 4 wk, mated, and ...
متن کاملGambling et al FETAL IRON STATUS REGULATES MATERNAL IRON METABOLISM DURING PREGNANCY IN THE RAT
Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn Aberdeen AB21 9SB, UK Biomathematics and Statistics Scotland, Rowett Institute of Nutrition and Health, Greenburn Road, Aberdeen AB21 9SB, UK Dept of Biochemistry and Molecular Biology, Royal Free Hospital, Rowland Hill Road, London NW3 2QG, UK Department of Hygiene and Human Nutrition, Agricultural Univ...
متن کاملFetal iron levels are regulated by maternal and fetal Hfe genotype and dietary iron.
BACKGROUND Iron metabolism during pregnancy maintains fetal iron levels at the expense of the mother. The mechanism behind this regulation is still not clear despite recent advances. Here we examine the role of maternal and fetal Hfe, its downstream signaling molecule, hepcidin and dietary iron in the regulation of placental iron transfer. DESIGN AND METHODS Hfe wild-type, knockout and hetero...
متن کاملIron supplementation, maternal packed cell volume, and fetal growth.
Previous studies have found that there is a correlation between mothers' haemoglobin concentration or packed cell volume and infants' birth weight, and that iron supplementation increases mothers' haemoglobin concentration. The purpose of this study, using the data of a large randomised trial on iron prophylaxis during pregnancy, was to find out whether iron supplementation causes fetal growth ...
متن کاملRole of iron supplementation in promoting maternal and fetal outcome
BACKGROUND The data comparing daily versus intermittent iron supplementation during pregnancy remain controversial. This study was undertaken to compare the efficacy of daily versus two different intermittent iron supplementation regimes on hematologic markers and birth outcomes in nonanemic pregnant women. METHODS Two hundred and ten women with singleton pregnancies, no known disease, and he...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2012
ISSN: 1732-2693
DOI: 10.5604/17322693.1019651